Hydrophobic Gating of Ion Permeation in Magnesium Channel CorA.
Ion channels catalyze ionic permeation across membranes via water-filled pores.To understand how chervo jacke herren changes in intracellular magnesium concentration regulate the influx of Mg2+ into cells, we examine early events in the relaxation of Mg2+ channel CorA toward its open state using massively-repeated molecular dynamics simulations con